在健康的成年人中,左心室的正常射出分数是多少? 一个基于人口的心声回声学研究的元分析
Anne Emilie Morsing1, Filip Gnesin2,3, Asya Lyass4
1Graduate School of Health, Aarhus University, Aarhus, Denmark.
Journal of cardiovascular imaging
|January 22, 2026
概括
正常的左心室喷射分数 (LVEF) 范围现在由性别和种族定义. 在健康的成年人中,LVEF低于50%不太可能是正常的,无论人口统计数据如何.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 公共卫生 公共卫生
背景情况:
- 通过心声学评估的左心室喷射率 (LVEF) 对预防心力衰竭至关重要.
- 正常LVEF的精确下限尚未得到确定的.
- 在不同人群中定义正常的LVEF范围是必不可少的.
研究的目的:
- 为了建立正常的LVEF范围,按性别,年龄和自我报告的种族/种族分层.
- 为了澄清健康成年人正常LVEF的下限.
- 为临床实践提供有关LVEF解释的信息.
主要方法:
- 基于人口的心声图谱研究 (2000-2025) 的 MEDLINE 系统文献搜索.
- 包括报告健康成年人LVEF平均值和标准偏差的研究.
- 来自10项研究的LVEF数据的元分析 (n=10,427).
主要成果:
- 聚合平均LVEF为62.8%,正常限值为51.8%-73.2%.
- 女性的LVEF平均值 (63.7%) 比男性 (61.9%) 高.
- 亚裔个体的LVEF较高;LVEF<50%在各小组中罕见 (<1-2%).
结论:
- 正常LVEF的下限约为女性的53%和男性的52%.
- 低于50%的LVEF极不可能代表正常的心脏功能.
- 由于显著的统计异质性,结果应谨慎解释.
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