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益生菌和健康学龄前儿童的发育进展:双盲,安慰剂控制的试验

Hafiz Haris Ahmad^1,2, Blake Peck¹, Daniel Terry^1,3,4

¹Institute of Health and Wellbeing, Federation University, Ballarat, Australia.

Nutritional neuroscience

|January 22, 2026

概括

益生菌补充剂没有显著影响健康学龄前儿童的发育进展. 虽然两组都出现了改善,但年龄和饮食是关键因素,这项研究没有足够的力量.

科学领域:

儿科健康儿科健康
微生物组研究微生物组研究
发展心理学发展心理学

背景情况:

肠-大脑轴表现出双向关系,影响整体健康.
益生菌对老年人的精神灵活性和压力有好处.
对益生菌对幼儿发育的影响的研究是有限的.

研究的目的:

评估益生菌补充剂对健康儿童发育进展的影响.
探索早期儿童对认知和行为发展的潜在影响.

主要方法:

这是一项为期六个月的前性,随机,双盲,安慰剂对照试验,涉及105名健康儿童.
参与者接受了益生菌或安慰剂,使用ASQ-3和ASQ:SE-2进行发育评估.
分析包括每项协议和基线年龄组比较.

主要成果:

益生菌和安慰剂组都在6个ASQ-3发育领域中的3个领域出现了改善.
44个月以上的儿童在基线显著改善发育成绩.
随着年龄的增长和更多的水果/蔬菜摄入量是发展的重要混因素.

结论:

益生菌补充剂没有显著影响健康学龄前儿童的发育进展.
该研究不足以检测到对主要结果的显著影响.
建议对不同种群进行进一步的大规模试验,以澄清益生菌的影响.

关键词:

益生菌益生菌是一种益生菌.孩子们的孩子们的孩子们的孩子们.临床试验临床试验临床试验临床试验临床试验认知认知认知发展进步发展进步幼儿教育幼儿教育幼儿教育我们的肠道微生物组.肠-大脑轴肠-大脑轴

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