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Updated: Jan 24, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

对创伤性脑损伤的专利审查 (2020-2025)

Khyati Sharma¹, Deepak Agrawal², Reema Gabrani¹

¹Centre for Emerging Diseases, Department of Biotechnology, Jaypee Institute of Information Technology, Noida, U.P., India.

The International journal of neuroscience

|January 23, 2026

概括

最近的专利活动显示了创伤性脑损伤 (TBI) 诊断和治疗方面的进展. 创新重点是通过生物标志物和多模式神经保护和恢复策略的早期检测.

科学领域:

神经科学是一个神经科学.
生物医学工程生物医学工程
药理学药理学是指药理学的学科.

背景情况:

创伤性脑损伤 (TBI) 是全球死亡和残疾的主要原因.
目前对TBI的治疗方法有限,缺乏阻止或逆转二次损伤级联的能力.
对于创伤创伤的新型诊断和治疗策略有着至关重要的需求.

研究的目的:

审查最近的创伤性脑损伤 (TBI) 专利活动 (2020-2025年).
突出TBI诊断,生物标志物整合和治疗策略方面的创新.
评估TBI研究和开发的转化潜力和未来方向.

主要方法:

从2020-2025年对专利文献进行分析,重点关注TBI.
专利被分类为诊断创新,生物标志物整合和治疗策略.
对新兴技术及其临床适用性的专家意见的审查.

主要成果:

诊断专利包括多式联络平台,结合生物标志物 (GFAP,UCH-L1,NfL,p-tau),成像和生理监测,用于早期检测和分层.
治疗专利涵盖抗炎药物,代谢稳定剂,再生方法和先进的药物输送系统.
综合神经保护,神经恢复和功能恢复的多模式治疗策略正在出现.
诸如呼吸传感器和眼睛追踪等非侵入性诊断技术正在推进临床检测.

结论:

最近的专利活动反映了TBI诊断和治疗方面的重大进展.
生物标志物驱动的诊断显示出对临床检测和治疗指导的翻译价值.
治疗创新虽然有前途,但大部分仍处于早期临床或临床前阶段.
多模式和再生方法代表了TBI治疗发展的未来.

关键词:

诊断工具诊断工具诊断工具药物输送是药物输送的过程.神经蛋白质是一种神经蛋白质.神经活性类固醇是一种神经活性类固醇.神经系统疾病神经系统疾病有针对性的治疗.

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