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Updated: Jan 24, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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在蛋白质中任意位置进行快速和高产的二硫化物生物结合

Dastgir Shakil Shaikh1, Suman Rajput1, Dimpy Kalia1

  • 1Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal Bypass Road, Bhauri, Bhopal, 462066 Madhya Pradesh, India.

Journal of the American Chemical Society
|January 23, 2026
PubMed
概括

新的StapleAld和LAP-StapleAld技术可以通过二硫化物链接高效地生物结合蛋白质. 这克服了现有方法的局限性,允许对广泛应用的蛋白质和进行特定的标记.

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