在一只狗的先天性神经瘤
Jesse Cole1, Paula A Schaffer1,2, Natalie M Kirk1,2
1Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA.
概括
一只年轻的莱昂伯格犬被诊断出一种罕见的先天性神经膜瘤. 这种瘤表现出独特的伪洋球形和多焦点黑色细胞分化,为犬类瘤学提供了洞察力.
科学领域:
- 兽医病理学 兽医病理学
- 狗类瘤学 狗类瘤学
- 新生病新发性疾病
背景情况:
- 狗的先天性质量并不常见.
- 神经瘤在狗群体中很少被描述.
- 早期发病的胸部质量需要彻底的组织病理学评估.
研究的目的:
- 在狗中鉴定先天性神经膜瘤的组织病理学和免疫组织化学特征.
- 为了记录一种罕见的犬类瘤性疾病病例.
- 为了解兽医学中罕见的瘤类型作出贡献.
主要方法:
- 胸腔质量活检的组织病理学检查.
- 针对质酸纤维蛋白,PGP9.5,S100,Sox10,拉米宁,NeuN,梅兰A和PNL2的免疫组织化学染色.
- 评估瘤细胞形态和排列,包括伪洋球形状.
主要成果:
- 该群体的特点是侵入性,未被封装的状细胞群体.
- 在瘤组织内观察到伪洋球形状.
- 免疫组织化学检查显示,质酸纤维蛋白和PGP9.5的标签很强,S100和Sox10的标签中度,NeuN,Melan A和PNL2.2的多焦点标签很强.
- 支持矩阵显示强烈的拉米林免疫标记.
结论:
- 组织病理学和免疫组织化学发现支持先天性神经膜瘤的诊断.
- 这一病例代表了这种瘤类型在狗中罕见的发生.
- 这些发现强调了对罕见犬类新生瘤的综合诊断技术的重要性.
相关概念视频
Nerve Supply of the GI Tract
3.4K
The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
3.4K
Spinal Nerves: Plexus II
2.2K
The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
2.2K
Cranial Nerves: Types Part I
4.9K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
4.9K
Cranial Nerves: Types Part II
4.7K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
4.7K
Spinal Nerves: Anatomy
8.4K
Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
8.4K
Spinal Nerves: Plexus I
2.6K
Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
2.6K


