多不和脂肪酸在对抗心血管炎症中的作用:使用CiteSpace和VOSviewer进行的图书识别和视觉分析
Yalin Huang1, Zhuoyi Zhang1, Tianzhang Zhang1
1Department of Cardiology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Endocrine, metabolic & immune disorders drug targets
|January 23, 2026
概括
对多不和脂肪酸 (PUFA) 和心血管炎症的研究表明持续增长. 新兴趋势侧重于肠道微生物群-PUFA轴,氧化应激,以及未来应用的亲解决途径.
科学领域:
- 生物医学科学 生物医学科学
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- 心血管炎症是一个重大的健康问题.
- 多不和脂肪酸 (PUFA) 在调节炎症过程中起着至关重要的作用.
- 了解PUFA和心血管炎症之间的相互作用对于疾病预防和治疗至关重要.
研究的目的:
- 分析当前关于多不和脂肪酸 (PUFA) 和心血管炎症的研究环境.
- 确定关键的研究热点,有影响力的机构和该领域的领先期刊.
- 绘制PUFA介导的心血管炎症研究中不断变化的趋势和新出现的机制.
主要方法:
- 从科学网络核心集合 (2009-2024) 中对文献进行图书法分析.
- 使用CiteSpace和VOSviewer进行数据可视化和分析.
- 专注于识别出版趋势,协作网络和引用影响.
主要成果:
- 在过去的15年里,关于PUFA和心血管炎症的出版物不断增加.
- 美国在研究成果方面处于领先地位,其中"营养素"是著名的期刊.
- 主要机构包括哈佛大学和加利福尼亚大学系统;强大的国际合作是显而易见的.
- 研究趋势突出显示了PUFA与炎症标志物,抗炎机制和疾病关联之间的关系.
- 欧米茄-3和欧米茄-6PUFAs对炎症和心血管疾病 (CVD) 风险表现出明显的影响.
- 新兴的研究重点是肠道微生物群在调解PUFA效应,氧化应激和亲解决途径方面的作用.
结论:
- 在PUFA和心血管炎症领域持续开展全球研究活动和合作.
- 肠道微生物群-PUFA轴,氧化应激和亲解决途径代表了关键的新兴研究领域.
- 这些发现表明,通过基于PUFA的干预措施来管理心血管炎症有显著的转化机会.
相关概念视频
Overview of Fatty Acid Metabolism
36.7K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
36.7K
Inflammation
61.8K
Overview
61.8K
Overview of the Cardiovascular System
11.1K
The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
11.1K
Regulation of the Cardiovascular System
3.8K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
3.8K
Exercise and Cardiovascular Response
3.9K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.9K
Psychoneuroimmunology: Cardiovascular Disease
429
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
429


