Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

5.2K
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
5.2K
Cell Size01:22

Cell Size

126.5K
Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
126.5K
Protein-protein Interfaces02:04

Protein-protein Interfaces

14.6K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.6K
Support Reactions in Three Dimensions01:27

Support Reactions in Three Dimensions

1.6K
Support reactions in three dimensions help maintain the stability and equilibrium of various structures and systems. These reactions prevent the system from translating and rotating, ensuring the design can withstand external forces and perform its intended function efficiently and safely. Some of the supports providing support reactions in three dimensions are discussed below:
Ball and Socket Joint is one of the supports allowing free rotation about any axis. This freedom of rotation is...
1.6K
Relative Velocity in One Dimension01:10

Relative Velocity in One Dimension

9.7K
The understanding of the concept of reference frames is essential to discuss relative motion in one or more dimensions. When we say that an object has a certain velocity, we must state the velocity with respect to a given reference frame. In most examples, this reference frame has been Earth. For instance, if a statement reads that a person is sitting in a train moving at 10 m/s east, then it implies that the person on the train is moving relative to the surface of Earth at this velocity,...
9.7K
Relative Velocity in Two Dimensions01:11

Relative Velocity in Two Dimensions

8.9K
Relative velocity is the velocity of an object as observed from a particular reference frame, or the velocity of one reference frame with respect to another reference frame. The concept of relative velocity can be used to describe motion in two dimensions. Consider a particle P and two reference frames S and S′. The position of the origin of S′ as measured in S is , the position of P as measured in S′ is , and the position of P as measured in S is , which can be evaluated by utilizing...
8.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Beyond MURANO: sequencing therapy in relapsed chronic lymphocytic leukaemia.

Lancet (London, England)·2026
Same author

Exploring Synergies in Brain-Machine Interfaces: Compression vs. Performance.

Restorative neurology and neuroscience·2026
Same author

Superior Induction of Apoptosis by Blue Light Compared to Red Light Photodynamic Therapy in Cutaneous Squamous Cell Carcinoma Keratinocytes.

Journal of biophotonics·2026
Same author

Sharp wave-ripple clusters enhance hippocampal-neocortical engagement for memory consolidation.

bioRxiv : the preprint server for biology·2026
Same author

Identification of the MRTFA/SRF pathway as a critical regulator of quiescence and chemotherapy resistance in cancer.

Cancer letters·2026
Same author

Antiviral Treatment of Herpes Simplex Virus Decreases the Risk of Alzheimer's Disease and Dementia.

Journal of drugs in dermatology : JDD·2026

相关实验视频

Updated: Jan 24, 2026

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
07:30

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

2.5K

微针透阵列与轴尺寸尺寸为无袖外围神经接口.

Dongxiao Yan1, Ahmad Jiman2, David Ratze1

  • 1University of Michigan Department of Electrical Engineering & Computer Science, Ann Arbor, MI, 48109 USA.

International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering
|January 23, 2026
PubMed
概括

研究人员开发了一种新的,超小型化的微针阵列,用于绘制小自主神经的地图. 这种没有袖子的装置提供了精确的控制和神经接口的独特手术技术.

更多相关视频

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

3.9K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.9K

相关实验视频

Last Updated: Jan 24, 2026

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
07:30

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

2.5K
Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

3.9K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.9K

科学领域:

  • 生物医学工程 生物医学工程
  • 神经科学是一个神经科学.
  • 材料科学 材料科学 材料科学

背景情况:

  • 自主神经对于交感和副交感控制至关重要,在器官目标附近的直径通常只有数百微米.
  • 现有的与小神经接口的方法通常涉及重的手,限制精度,并可能造成损伤.

研究的目的:

  • 设计和制造一个超小型的,没有袖口的微针阵列,用于绘制小自主神经的地图.
  • 开发一种新的外科手术技术,用于安全,无袖的微针阵列植入.

主要方法:

  • 在基板上制造高密度微针阵列 (25-100针),具有1微米尖端和双收缩轴.
  • 控制针尖和轴角,以获得最佳的度和刚度.
  • 开发一种使用光化学粘合的手术技术,将原蛋白/孟加拉粘合剂粘合到epineurium上,用于无袖阵列固定.

主要成果:

  • 展示了具有可控制针形状的阵列,以及在弹性基板上稳定的后侧.
  • 成功制造出能够围绕300微米神经包裹的阵列.
  • 提出了一种可行的手术方法,可以在没有袖口的情况下植入0.3mm x 1.2mm小的阵列.

结论:

  • 开发的超小型化微针阵列和手术技术对精确地绘制小自主神经的准确绘制有希望.
  • 这种无袖子的方法比传统的神经接口方法提供了潜在的进步.
  • 未来的研究将涉及在老鼠迷走神经模型中的设备功能化和验证.