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Updated: Jan 24, 2026

Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages
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Published on: April 6, 2022

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由ShigellaOspC2和OspC3对人体热酶Caspase-5和Caspase-4的差异化向

Kyungsub Kim, Marcos Antonio Valdespino Diaz, Rowan Karr

    bioRxiv : the preprint server for biology
    |January 23, 2026
    PubMed
    概括

    希格拉菌通过使用OspC蛋白来禁用特定的caspases (CASP4和CASP5) 来阻止宿主细胞死亡. 一个新的Pyroptotic Caspase Specificity (PCS) 域决定了这种向,提供了治疗洞察力.

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