相关实验视频

Updated: Jan 24, 2026

Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants
09:16

Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants

Published on: February 21, 2015

20.4K

扩展基因组在一个瓶中的真相:检测和验证使用高精度NanoSeq的新型低频变异

Yang Zhang, Hsu Chao, Muchun Niu

    bioRxiv : the preprint server for biology
    |January 23, 2026
    PubMed
    概括

    这项研究优化了NanoSeq双重测序用于全基因组体质突变发现. 新的NanoSeq-MBN方法实现了高精度和覆盖范围,使得用于临床应用的超罕见突变的检测成为可能.

    更多相关视频

    Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency18:10

    Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

    Published on: June 16, 2011

    30.1K
    A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes09:10

    A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

    Published on: May 22, 2018

    10.0K

    相关概念视频

    Reliability and Validity01:29

    Reliability and Validity

    Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
    13.8K
    Improving Translational Accuracy02:07

    Improving Translational Accuracy

    Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
    14.1K
    Improving Translational Accuracy02:07

    Improving Translational Accuracy

    3.6K
    Uncertainty in Measurement: Accuracy and Precision03:37

    Uncertainty in Measurement: Accuracy and Precision

    Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
    100.5K
    Histone Variants at the Centromere02:30

    Histone Variants at the Centromere

    Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
    5.0K
    Genomics02:02

    Genomics

    Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
    39.8K