相关实验视频

Updated: Jan 24, 2026

Using Microfluidic Devices to Measure Lifespan and Cellular Phenotypes in Single Budding Yeast Cells
09:18

Using Microfluidic Devices to Measure Lifespan and Cellular Phenotypes in Single Budding Yeast Cells

Published on: March 30, 2017

8.2K

蛋白质酶激活剂Blm10维持细胞蛋白质平衡和结合体质量在芽的酵母酵母

Maia C Reyes, Diego R Ramos-Ortiz, Jiarong A Cheng

    bioRxiv : the preprint server for biology
    |January 23, 2026
    PubMed
    概括

    Blm10蛋白微调酵母细胞生成过程中的蛋白酶体活性,保护蛋白质稳定和细胞体适应性. 它的缺失会导致蛋白质静止应激,并损害细胞复发.

    更多相关视频

    Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast10:41

    Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast

    Published on: August 20, 2013

    13.3K
    Quantifying Subcellular Ubiquitin-proteasome Activity in the Rodent Brain09:25

    Quantifying Subcellular Ubiquitin-proteasome Activity in the Rodent Brain

    Published on: May 21, 2019

    7.2K

    相关概念视频

    The Proteasome02:18

    The Proteasome

    Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
    In this pathway, the target proteins are first tagged with small proteins called ubiquitin. A series of enzymes carry out the ubiquitination of the target proteins - E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3...
    10.1K
    The Proteasome01:13

    The Proteasome

    Eukaryotic cells can degrade proteins through several pathways. One of the most important among these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
    In this pathway, the target proteins are first tagged with small proteins called ubiquitin. This involves participation of a series of enzymes including— E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3...
    1.7K
    The Proteasome02:18

    The Proteasome

    4.5K
    Yeast Signaling01:28

    Yeast Signaling

    Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
    17.2K
    Balancing Redox Equations02:58

    Balancing Redox Equations

    Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
    61.7K
    The Proteasome Structure01:17

    The Proteasome Structure

    The ubiquitin-proteasome pathway is a well-known mechanism utilized by eukaryotic cells to remove cytoplasmic proteins that are misfolded, damaged, or no longer needed. In this pathway, the protein that needs to be eliminated undergoes a process called ubiquitination, where a chain of ubiquitin molecules is attached to the 48th lysine residue of the target protein. This ubiquitin modification helps the proteasome distinguish between a target protein and a healthy protein.
    The proteasome is an...
    1.6K