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Updated: Jan 24, 2026

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由IL-17受体 hetero-tetramer诱导的ACT1寡合化的结构基础

Hui Zhang, Xiao-Chen Bai, Xuewu Zhang

    bioRxiv : the preprint server for biology
    |January 23, 2026
    PubMed
    概括

    介素-17受体 (IL-17Rs) 通过它们的SEFIR域与ACT1形成信号复合体. 这项研究揭示了冷-EM结构,揭示了IL-17RA和IL-17RB如何与ACT1组装在一起以调节免疫信号.

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