增长迟缓儿童的内镜和组织病理学发现
1Division of Pediatric Gastroenterology, Department of Child Health and Diseases, Kahramanmaras City Hospital, Kahramanmaras, Turkiye.
Northern clinics of Istanbul
|January 23, 2026
概括
内镜评估显示,在所有患有持续增长迟缓的儿童中,即使没有典型症状,也发现了显著的胃肠道发现. 这些结果强调了内镜在诊断导致儿科患者生长不良的潜在疾病方面的重要性.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 临床营养学 临床营养学
- 诊断内镜检查 诊断内镜检查
背景情况:
- 儿童的增长迟缓可能源于各种潜在的疾病.
- 充分的热量支持至关重要,但持续的生长问题需要进一步调查.
- 确定生长失败的根本原因对于有效的干预至关重要.
研究的目的:
- 描述经历生长迟缓的儿童的临床,内镜和组织病理特征.
- 调查上部胃肠道内镜在评估患有持续生长衰竭的儿科患者中的有用性.
- 为了确定这个队列中特定胃肠道疾病的流行率.
主要方法:
- 包括90名儿童 (2-18岁) 的队列,尽管至少3个月摄入了足够的热量,但仍有增长迟缓.
- 所有参与者都接受了食道胃管腺镜检查 (EGD),以诊断目的.
- 收集和分析了临床数据,包括营养状况,症状和实验室结果 (腹抗体,铁,B12水平).
主要成果:
- 大多数患者表现为营养不良 (88.9%),常见的内镜检查结果包括胃肠炎 (88.9%),十二指肠炎 (61.1%),胆汁反流 (35.6%).
- 组织病理学检查显示,慢性Helicobacter pylori胃炎 (72.2%),腹病 (20.0%) 和逆流食道炎 (17.8%) 的发病率很高.
- 重要的是,在所有儿童中都存在显著的内镜发现,无论伴随的消化不良症状如何,并且在H. pylori胃炎和营养状况或缺陷之间没有发现任何关联.
结论:
- 内镜检查是识别患有持续增长迟缓的儿童的胃肠道病理的宝贵工具,即使没有明显的症状.
- 这些发现强调了在儿童生长衰竭的诊断工作中考虑内镜评估的必要性.
- 需要进一步的研究,以充分阐明内镜在这种患者群体中的作用和最佳应用.
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