患者报告的症状和紧急医疗保健在神经内分泌瘤中的使用
Julie Hallet1,2,3,4, Christopher Noel1, Rinku Sutradhar2
1Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Endocrine oncology (Bristol, England)
|January 23, 2026
概括
患者报告的症状,如疼痛和不良幸福感,与神经内分泌瘤 (NET) 患者的紧急医疗保健使用有关. 监测这些症状可以帮助识别那些需要更好的症状管理的人,并减少急诊.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 医疗保健管理的管理
背景情况:
- 神经内分泌瘤 (NETs) 经常导致持续的症状,影响患者的生活质量.
- 患者报告的结果指标 (PROM) 被收集,但很少驱动临床干预.
- 了解症状与医疗保健利用之间的联系对于改善PROM实用性至关重要.
研究的目的:
- 调查患者报告的症状与被诊断为NETs的个体紧急医疗使用之间的关联.
- 确定通过埃德蒙顿症状评估系统 (ESAS) 测量的症状负担是否预测短期紧急医疗保健需求.
主要方法:
- 一项人口水平的回顾性队列研究,涉及2010-2019年间被诊断患有NET的成年人.
- 埃德蒙顿症状评估系统 (ESAS) 在诊断后两年内的得分被用作暴露.
- 在ESAS评估后的14天内,紧急医疗利用 (急诊室访问或计划外入院) 是主要结果,使用后勤回归分析.
主要成果:
- 分析了4000多名患者和19000份ESAS评估结果.
- 特定症状的增加,如昏昏欲睡,食欲不振,疼痛和不良的幸福感显著与更高的紧急医疗保健使用率有关.
- 综合高ESAS评分显示,每增加1分,紧急医疗使用的几率增加21%.
结论:
- 在NET患者中,ESAS得分是随后短期紧急医疗保健使用的重要预测指标.
- 结果表明,在管理门诊症状方面存在潜在的差距,突出显示了需要主动干预的必要性.
- 常规监测ESAS得分可以识别需要加强症状管理以防止紧急医疗接触的高风险患者.
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