从聚碳酸-尿和其他植入物生物材料的关节软骨磨损的比较
Maha Ead1, Andrea Dimitrov2,3, Haoyang Li1
1Department of Mechanical Engineering, University of Alberta, Edmonton, Canada.
概括
聚碳酸盐-尿 (PCU) 显示了与塔拉尔植入物材料相比,关节软骨 (AC) 的磨损最小. 这种生物材料是关节置换手术的有希望的候选人,最大限度地减少了脚关节软骨的损伤.
科学领域:
- 生物材料科学 生物材料科学
- 整形外科手术 整形外科手术
- 磨损分析 磨损分析
背景情况:
- 关节置换手术是有效的关节骨硬化与崩.
- 关节软骨 (AC) 磨损是一个问题,当人工骨假肢与本地脚软骨相互作用时.
研究的目的:
- 为了评估关节软骨 (AC) 磨损与塔拉尔植入物的各种生物材料.
- 为了确定最佳的生物材料,以替换骨手术,尽量减少软骨损伤.
主要方法:
- 在体外双运动磨损测试五种生物材料 (Co-28Cr-6Mo,Ti-6Al-4V,UHMWPE,PEEK,PCU) 对猪AC.
- 在牛血清中浸泡测试为43,200个周期在3赫兹.
- 宏观 (外桥) 和微观 (OARSI) 分级以量化软骨磨损.
主要成果:
- 宏观分析:Ti-6Al-4V显示了最多的交流磨损,其次是Co-28Cr-6Mo,PEEK,UHMWPE和PCU.
- 微观分析:PEEK显示了最多的交流磨损,其次是Ti-6Al-4V,Co-28Cr-6Mo,UHMWPE和PCU.
- PCU显示AC磨损最少,与软骨对软骨对照相比没有显著差异.
结论:
- 聚碳酸尿 (PCU) 显示出卓越的关节软骨 (AC) 磨损性能.
- 由于AC磨损最小,PCU是塔拉尔植入物涂层的合适候选材料.
- 这一发现支持开发具有增强生物相容性的先进口腔假肢.
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