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Updated: Jan 24, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
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Published on: September 27, 2017

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设计,合成和评估一种强效和选择性的ROCK2抑制剂,用于治疗无氧性皮肤炎.

Churu Mao1, Shuai Zhan1, Zhangyun Fang1

  • 1Institute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan 316021, China.

Journal of medicinal chemistry
|January 23, 2026
PubMed
概括

一种新药,10d针对ROCK2治疗亚托皮性皮肤炎 (AD). 这种选择性抑制剂通过降低S100A9的调节,在临床前模型中显示出卓越的疗效和安全性,为AD提供了一种新的治疗方法.

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