耳的改变淋巴功能:与认知的关联和rTMS的影响
Weijie Ye1,2, Yinjuan Du3, Shuo Li4
1Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
The Laryngoscope
|January 23, 2026
概括
淋巴系统功能障碍与耳和认知能力下降有关. 重复的横磁刺激 (rTMS) 治疗可以改善淋巴功能,减少耳的严重程度.
科学领域:
- 神经科学是一个神经科学.
- 放射学 放射学是一门学科.
- 神经学 神经学
背景情况:
- 耳是一种常见的听力障碍,通常与神经相关疾病有关.
- 淋巴系统功能障碍与各种神经疾病有关,但其在耳中的作用尚不清楚.
研究的目的:
- 调查 tinnitus,淋巴系统功能障碍和认知能力下降之间的关联.
- 评估重复性跨磁刺激 (rTMS) 对声患者淋巴功能的影响.
主要方法:
- 多模磁共振成像 (MRI) 索引包括状体体积 (CPV),扩大周围脉空间 (EPVS),周围脉空间 (DTI-ALPS) 的扩散张力图像分析和自由水 (FW) 用于评估淋巴功能.
- 认知功能使用Trail Making Test B (TMT-B) 进行评估.
- 耳的严重程度使用耳障碍问卷 (THQ) 进行测量.
主要成果:
- 与健康对照组相比,耳患者的DTI-ALPS指数降低,CPV增加.
- 升高的CPV与执行功能受损相关,而降低的ALPS指数与增加的耳严重程度相关.
- rTMS治疗导致自由水值降低和ALPS指数增加,同时降低了耳的严重程度.
结论:
- 淋巴功能障碍与耳有关,可能导致认知能力下降.
- rTMS治疗通过改善淋巴功能和缓解耳症状,显示出潜在的治疗益处.
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