描述家长对B型急性淋巴细胞白血病儿童治疗的持久影响的担忧
Kellee N Parker1, Sarah W Alexander2, Lisa M Jacola3
1Division of Hematology/Oncology/BMT, Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Pediatric blood & cancer
|January 23, 2026
概括
患有B型急性淋巴细胞白血病 (B-ALL) 的孩子的父母非常担心神经认知缺陷等长期影响. 这些问题影响了家庭,并强调了需要更好的信息和父母参与研究的需要.
科学领域:
- 儿科瘤学 儿科瘤学
- 癌症的生存率 癌症的生存率
- 儿童癌症研究 儿童癌症研究
背景情况:
- 乙级急性淋巴细胞白血病 (B-ALL) 是最常见的儿科癌症.
- 虽然治愈是常见的,但B-ALL疗法会导致长期的毒性.
- 了解父母对晚期影响的担忧对于支持和治疗进化至关重要.
研究的目的:
- 调查父母对B-ALL治疗晚期影响的担忧.
- 为了识别导致家长最担心的特定后期影响.
- 了解这些担忧与孩子和父母因素的相关性.
主要方法:
- 对442名患有B-ALL.儿童的家长进行了在线调查.
- 父母发现并评价了对潜在的晚期影响的担忧.
- 定量和定性分析探讨了关联和主题.
主要成果:
- 神经认知缺陷,二次癌症,心理健康变化,心脏毒性和不孕症是最令人担忧的问题.
- 对神经认知缺陷的担忧更高的是年幼孩子的父母.
- 父母对晚期影响的担忧造成了持久的焦虑,并影响了日常生活.
结论:
- 父母对B-ALL晚期影响,特别是神经认知障碍表示严重和持续的担忧.
- 需要改善父母对B-ALL晚期影响的指导.
- 整合家长的观点对于优先考虑B-ALL研究至关重要.
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