小反动物的间歇性肺病
1Veterinary Sciences Centre, School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
概括
绵羊和山羊的间歇性肺部疾病导致全球健康和经济损失显著. 本综述详细介绍了各种传染性,寄生性和有毒的病原体,这些病原体是造成这些衰弱的肺部疾病的原因.
科学领域:
- 兽医病理学 兽医病理学
- 肺部病理学 肺部病理学
- 小小的反动物医学
背景情况:
- 绵羊和山羊的间歇性肺病 (ILD) 对动物健康,福利和农业生产力构成重大全球挑战.
- 特定的ILD如小动物瘟疫 (PPR),动物性肺炎,maedi和绵羊肺腺癌具有严重的经济和生计影响,特别是在受影响的农业社区.
- 这些疾病向肺间歇体,导致对酶体损伤和临床表现.
研究的目的:
- 在小反动物中全面审查与各种引起ILD的病原体相关的病原和病变.
- 阐明由病毒,细菌,寄生虫和有毒病因引起的肺损伤机制.
- 提供对影响肺间歇体的病理结果的详细了解.
主要方法:
- 审查关于羊和山羊ILDs的现有文献.
- 病理性病变和病原遗传机制的详细描述.
- 病原体的分类,包括病毒,细菌,寄生虫和有毒因素.
主要成果:
- 小反动物的隐形病毒感染会通过淋巴细胞和巨细胞的透引起逐渐的气膜壁扭曲.
- 比伯斯蒂尼亚特雷哈洛西 (Bibersteinia trehalosi) 感染导致急性气膜隔膜血栓栓塞.
- 在幼虫迁徙过程中,Dictyocaulus filaria的寄生会导致以奥西诺菲尔为媒介的膜壁亡.
- 绵羊肺腺癌涉及瘤II型肺细胞在间歇性支架上.
- 植物的有毒伤害 (特雷玛,克罗塔拉里亚物种). 和化学物质 (碳酸,3-甲基) 影响肺间隙.
结论:
- 多种各样的病原体有助于小反动物的ILD,每个病原体都有不同的致病性途径和由此产生的病变.
- 了解这些多样化的机制对于准确诊断和有效管理绵羊和山羊肺部疾病至关重要.
- 本次审查巩固了关于ILDs的知识,突出了它们对动物健康和农业可持续性的影响.
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