血静粉用于非恶性上胃肠道出血:随机对照试验的系统审查和元分析
Paula Santo1, Gilmara Coelho Meine2, Renan Martins Gomes Prado3
1Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Journal of gastroenterology and hepatology
|January 23, 2026
概括
与标准内镜治疗 (SET) 相比,静血粉 (HP) 显示,在非变节性上部胃肠道出血 (NVUGIB) 的内镜手术中,与非出血可见血管相比,进一步出血的风险较低. 在两种治疗方法中,复出率相似.
科学领域:
- 胃肠病学 胃肠病学
- 进行内镜干预.
- 胃肠道出血管理 胃肠道出血管理
背景情况:
- 标准内镜治疗 (SET) 对于非的上部胃肠道出血 (NVUGIB) 的有效性有所不同.
- 静血粉 (HP) 对恶性病变有希望,但其对良性NVUGIB的疗效尚不清楚.
研究的目的:
- 为了比较HP与SET的有效性,作为非恶性NVUGIB的第一线治疗.
- 评估HP在控制良性上部胃肠病变出血方面的疗效.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析来源于PubMed,Embase和Cochrane图书馆.
- 从创立到2025年1月的数据库进行了搜索.
- 分析了使用风险比率 (RR) 的二进制结果和使用平均差异 (MD) 的连续结果,具有95%的置信区间 (CI).
主要成果:
- 包括5个RCT与708名患者.
- 在食管胃二透镜 (EGD) 期间,HP显示出进一步出血的风险略低 (RR 1.04; p=0.04).
- 没有观察到重出血率,需要第二次治疗或手术时间的显著差异. 亚组分析表明,HP的益处仅限于Forrest IIa病变,而不是活性出血.
结论:
- 在非恶性NVUGIB患者中,HP在EGD期间显示出进一步出血的风险降低,可见血管没有出血.
- 对于活跃出血的EGD期间的进一步出血或在不同时间点 (1-30天) 的再出血风险没有显著差异.
相关概念视频
Random and Systematic Errors
14.6K
Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
14.6K
Review and Preview
8.3K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.3K
Review and Preview
10.9K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.9K
Statistical Software for Data Analysis and Clinical Trials
1.4K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
Bleeding in Fresh Concrete
557
Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
557
Anatomy of the Gastrointestinal System
2.7K
The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
Here's a detailed walkthrough of this complex system:
2.7K


