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Updated: Jan 24, 2026

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通过分子动力学和实验阐明在不同可压缩接口的机械应力下蛋白质粒子形成的机制

Tim Sarter1, Athanasia Karavalasi2, Wolfgang Friess1

  • 1Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Munich 81377, Germany.

Molecular pharmaceutics
|January 23, 2026
PubMed
概括

压缩界面上的机械应力,如空气-液体和-液体,可以导致蛋白质聚合. 这项研究揭示了-液体接口促进更多的粒子形成比空气-液体接口由于更强的蛋白质结合.

关键词:
空气 - 液体接口接口这是一种配方配方.接口 接口 接口 接口 接口机械应力 机械应力 机械应力分子动力学分子动力学蛋白质聚合蛋白质的聚合物,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

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