输入比对双输入腔肺辅助装置的影响
Simon Klocker1, Leon Ballabani1, Pascal Schmidt1
1From the Department of Cardiac and Thoracic Aortic Surgery, Medical University of Vienna, Austria.
概括
一种新的腔肺辅助装置 (CPAD) 显示了可靠的液压性能和在各种输入比率上的血相容性. 这种设备可以准确监测流量,支持Fontan循环患者.
科学领域:
- 生物医学工程 生物医学工程
- 心血管器械 心血管器械
- 血液动力学 血液动力学
背景情况:
- 喷泉循环是单性心脏病的息治疗方法,但它容易导致血液动力学衰竭.
- 为了解决这些局限性,开发了一种具有双入口的新型腔肺辅助装置 (CPAD).
研究的目的:
- 调查不同输入比 (IR) 对双入口CPAD的液压性能,血液相容性和流量估计精度的影响.
- 评估CPAD在丰田患者相关的各种生理条件的可靠性.
主要方法:
- 液压性能 (H-Q特性) 在不同的IR中经过实验和数值评估.
- 血液溶解被实验评估,血液相容性指标被数值确定.
- 使用电机电流,转速和粘度对流量估计的准确性在不同的IR下进行了检查.
主要成果:
- 在所有测试的IR中,CPAD显示了液压性能 (ΔH < 2.2 mm Hg) 和血液溶解 (NIH: 22.4%,DI: 4.9%) 的最小变化.
- 流量估计模型证明非常准确,无论IR,RMSE<0.148 L/min和R2>0.99.
- 双入口CPAD在研究的IR中表现出可靠的性能.
结论:
- 双入口CPAD在广泛的输入比率中可靠地运行,这表明它适合各种患者群体.
- 该设备的稳定性能和精确的流量监测能力支持其在改善Fontan循环管理方面的潜在应用.
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