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用利法西明进行肠道去污染减轻了小鼠的LSEC功能障碍和肝纤维化

Tingting Su1, Sanchuan Lai2, Hongtan Chen1

  • 1Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

PloS one
|January 23, 2026
PubMed
概括

肝硬化中肠道微生物组的变化使更多有害的脂多糖 (LPS) 能够到达肝细胞. 利法西明治疗通过恢复肠道细菌和减少LPS来改善肝脏健康,从而缓解肝纤维化.

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