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Updated: Jan 25, 2026

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加拿大老龄化纵向研究 (CLSA) 中肺炎球菌疫苗覆盖率的变化:基于2018-2021年后续2调查的分析
Giorgia Sulis1,2, Nawal Maredia1, Christina Wolfson3,4
1Faculty of Medicine, School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.
PloS one
|January 23, 2026
概括
加拿大的肺炎球菌疫苗接种覆盖率仍然很低,只有56.8%的老年人和19.3%的慢性疾病患者接种了疫苗. 在2015-2021年间,覆盖率的增长很小,这凸显了改善公共卫生战略的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 肺炎球菌疫苗接种对于老年人和患有慢性病症 (CMC) 的个人至关重要,因为具有高侵袭性肺炎球菌疾病 (IPD) 风险.
- 加拿大肺炎球菌疫苗接种覆盖率不足于2025年全国80%的目标.
- 来自加拿大老龄化纵向研究 (CLSA) 的最新数据分析提供了最新的覆盖率估计,并确定了差异.
研究的目的:
- 用CLSA数据估计2018-2021年在符合条件的加拿大成年人中肺炎球菌疫苗的覆盖率.
- 为了确定疫苗接种率的社会人口学差异.
- 分析自2015年以来肺炎球菌疫苗接种范围的变化.
主要方法:
- 从CLSA FUP2 (2018-2021) 来自自行报告的肺炎球菌疫苗接种状态的横截面分析.
- 根据社会人口因素分层,流感疫苗接种和医疗保健联系.
- 与FUP1 (2015-2018) 相比,物流回归以确定与新疫苗接种相关的因素.
主要成果:
- 肺炎球菌疫苗覆盖率在65岁以上的成年人中为56.8%,在65岁以下的CMC患者中为19.3% (2018-2021年).
- 在男性,农村居民和特定省份的人口中观察到较低的疫苗接种率.
- 自2015年以来,新接种疫苗增加了28.4% (≥65) 和11% (<65有CMC);流感疫苗接种与肺炎球菌疫苗接种的几率更高有关.
结论:
- 在65岁以上的加拿大成年人中,肺炎球菌疫苗的覆盖率在2015-2018年和2018-2021年之间仅增加了2%.
- 在65岁以下有潜在疾病的成年人中,没有观察到覆盖范围的显著变化.
- 持续低覆盖率表明需要加强公共卫生干预措施,以实现国家疫苗接种目标.
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