自封式有效消毒污染的保留在整形外科手术托盘中的水泥
Andrew L Thomson1, Christina Chao1, Mohammad Hammad1
1Arthroplasty Research Laboratory, Research Institute, Hospital for Special Surgery, New York, NY.
The Journal of bone and joint surgery. American volume
|January 23, 2026
概括
标准的自闭包系统有效消毒聚甲基甲酸盐 (PMMA) 和受污染的手术仪器. 这确保保留的PMMA碎片不会在手术室中造成细菌污染的风险.
科学领域:
- 整形外科 整形外科 整形外科
- 手术感染控制手术感染控制
- 生物医学工程 生物医学工程
背景情况:
- 在手术仪器上保留的聚甲基甲酸盐 (PMMA) 在关节塑形术中越来越令人担忧.
- 之前的研究没有证实在自封后保留的PMMA上的细菌活力.
研究的目的:
- 为了确定临床自闭塞协议是否可以有效地消毒PMMA表面和被生物膜污染的仪器.
- 在标准灭菌程序后评估PMMA上的细菌活力.
主要方法:
- 黄金葡萄球菌和大肠杆菌的生物膜是在PMMA优惠券 (光滑和裂纹) 和螺丝上培养的.
- 样品接受了三个临床自闭馆灭菌方案.
- 使用殖民地形成单位 (CFU) 计数和腺三酸盐 (ATP) 水平来评估细菌活力.
主要成果:
- 非自化PMMA显示高细菌污染 (高达4.1 x 10^6 CFU/mL).
- 在自封后,所有PMMA表面,裂和螺丝都显示微不足道的活性细菌 (<10 CFU/mL和<5 RLU).
- 扫描电子显微镜证实生物膜结构保持完整,但缺乏活力细菌.
结论:
- 临床自闭包协议在杀菌PMMA和PMMA污染的手术仪器方面是有效的.
- 保留的PMMA和正在进行自闭式封闭的仪器不含活性的细菌,确保手术安全.
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