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Updated: Jan 25, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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一种含有Tudor域的蛋白质TDRD3调节Klf2依赖的T分化和功能,以调节免疫耐受性

Yun Shi1, Xiaoqun Tao2, Lei Shen2

  • 1Department of Immunology & Theranostics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

Science advances
|January 23, 2026
PubMed
概括

图多域含有蛋白3 (TDRD3) 对于免疫耐受性至关重要. 它的缺失会损害调节性T细胞的分化和功能,导致炎症,并突出TDRD3作为治疗点.

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