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Updated: Jan 25, 2026

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通过PDX模型和线粒体向,在儿科急性髓性白血病中推进精确治疗

Ambra Da Ros1, Alberto Peloso1, Giorgia Longo1

  • 1University of Padova, Padova, Italy.

Blood advances
|January 23, 2026
PubMed
概括

开发用于复发/耐药儿科急性髓性白血病 (pAML) 的新疗法至关重要. 患者衍生异种移植 (PDXs) 有效地模拟了pAML,使其能够识别新药组合,如Venetoclax和IACS-010759用于KMT2A重组的AML.

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