在和/或岛屿瘤中出现状症状:一项医院队列研究
Fredrik K Andersson1, Bisrat Ezra2, Kenney Roy Roodakker3
1Department of Neurology and Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.
Epilepsy & behavior : E&B
|January 23, 2026
概括
罕见的发作症状,如狂喜发作 (EcS) 和虚幻般的经历比以前认为的更为常见,特别是在和岛屿瘤患者中. 积极评估对于诊断和理解意识至关重要.
科学领域:
- 神经科学是一个神经科学.
- 发病学 (Epileptology) 是一个专业的学科.
- 精神病学是一个精神病学.
背景情况:
- 狂喜发作 (EcS) 与前面的岛屿网络有关,这对于自我处理至关重要.
- 在和岛屿病理学中,EcS和相关现象的频率仍未得到充分研究.
研究的目的:
- 调查患者ECS的患病率和临床特征.
- 为了探索岛屿瘤患者中狂喜症状的发生.
主要方法:
- 调查问卷分发给200名患者和40名岛屿瘤患者.
- 报告有相关症状的患者接受了面试和医疗记录分析 (EEG,成像).
- 类似于数字的症状包括超自然,宗教,精神,神秘或狂喜的体验.
主要成果:
- 在83名响应者中,5名 (6.0%) 符合面试资格;23名岛屿瘤响应者中的2名 (8.7%) 报告了相关症状 (两者都患有).
- 识别的体验包括EcS (n=1),ictal体外体验 (OBE) (n=2),以及ictal感知存在 (SenP) (n=5).
- SenP与右半球发作起源有关,包括岛瘤和 mesial 时硬化症.
结论:
- 类似numinous的发作体验相对比较常见,并且由于患者的不情愿和诊断重要性,需要积极的临床评估.
- EcS和OBE与不同的自我处理网络有关; SenP需要进一步研究其认知和神经生物学基础.
- 这些发现提供了对意识和主观实验经验的神经生物学的见解.
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