性病史预测持续的避孕套不使用和伴侣艾滋病毒血清转换在中国老年人与艾滋病毒:一个回顾性队列调解分析
Chunxing Tao1, Ting Huang1, Qingyi Liu2
1Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Public health
|January 23, 2026
概括
艾滋病毒感染的老年人和有性传播疾病 (STD) 病史的人有更高的风险使用不一致的避孕套并将艾滋病毒传播给伴侣. 将性病史纳入护理中对于管理老龄化艾滋病毒人群的性风险至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 艾滋病毒感染人口老龄化在管理性健康和传播风险方面提出了独特的挑战.
- 了解以前的性传播疾病 (STD) 史和正在进行的传播行为之间的相互作用对于有效的艾滋病毒预防策略至关重要.
研究的目的:
- 评估性病史对避孕套使用模式的影响,以及在中国西南地区被诊断患有艾滋病毒的老年人中,艾滋病毒传播到伴侣的风险.
主要方法:
- 一项回顾性队列研究利用了2003-2023年中国艾滋病毒/艾滋病综合应对信息管理系统 (CRIMS) 的数据.
- 包括新诊断出艾滋病毒的老年人 (≥50岁) 和有记录的性传播疾病史,分析了不一致的避孕套使用和伴侣艾滋病毒血清转化.
- 使用后勤回归和调解分析来检查性病史与血清转化关系中的避孕套使用的关联和作用.
主要成果:
- 在30492名艾滋病毒感染的老年人中,7.3%的人有经过记录的性传播疾病史.
- 性病史与不一致的避孕套使用 (aOR: 2.18) 和伴侣艾滋病毒血清转化风险增加 (aOR: 1.90) 有关.
- 不一致的避孕套使用部分调解了性病史和伴侣血清转换之间的关系,占总效应的11.9%.
结论:
- 在艾滋病毒感染的老年人中,先前的性病暴露与持续的性风险行为和对伴侣的艾滋病毒传播率更高有关.
- 将性病史评估纳入常规护理和长期监测,对于在艾滋病毒人口老龄化地区的血清异常伙伴关系至关重要.
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