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Updated: Jan 25, 2026

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides
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Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides

Published on: November 24, 2010

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MYC与新生RNA结合抑制R-循环衍生的RNA-DNA混合体的先天免疫信号

Leonie Uhl1, Amel Aziba1, Sinah Löbbert2

  • 1Theodor Boveri Institute, Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

Cell
|January 23, 2026
PubMed
概括

在细胞应激过程中,MYC基蛋白经历相变,转移到RNA. 这种由RNA驱动的反应抑制了免疫性RNA-DNA混合体,这对瘤生长至关重要.

关键词:
其他国家在 PDAC在 R 循环结合RNA一个TBK1在TLR3外体细胞天生的免疫信号胰腺管腺癌

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