肌肉-大脑轴机制将社区运动与老年人的认知功能联系起来:一个五臂随机对照试验
Jiadong Qiu1, Xiongying Song2, Jian Wang2
1Department of Sports Science, Hanyang University, Seoul, Republic of Korea.
Experimental gerontology
|January 23, 2026
概括
社区可行的练习,如陈式太极拳 (CTC12) 和广场舞 (SD),在老年人中适度改善了认知能力. 这些练习还显示出明显的生理变化,可能与肌肉-大脑轴有关.
科学领域:
- 老年学和运动科学
- 神经科学和肌肉生理学
- 公共卫生与老龄化问题
背景情况:
- 认知能力下降是老年人群的一个重大问题.
- 了解运动对认知和潜在机制的影响至关重要.
- 肌肉-大脑轴为运动干预提供了一个潜在的途径.
研究的目的:
- 为了比较社区可行的练习对老年人的认知功能的影响.
- 研究与这些炼相关的生理机制,特别是肌肉-大脑轴.
- 为老年人选择运动提供基于证据的指导.
主要方法:
- 一个单盲,五臂随机对照试验,涉及113名老年人.
- 干预包括12个形式的陈式太极拳 (CTC12),24个形式的式太极拳 (TC24),方形舞蹈 (SD),步行和一个控制组12周.
- 认知 (MoCA),身体组成 (SMM,FM,BMR),身体表现 (SPPB,HGS) 和血液生物标志物 (IL-6) 被评估.
主要成果:
- 在CTC12和SD组中,MoCA得分显著改善 (p<0.005).
- CTC12增加了骨肌肉质量 (SMM) 和基础代谢率 (BMR),降低了IL-6.
- SD降低了体重指数 (BMI) 和脂肪质量 (FM),并增加了BMR和SPPB.
结论:
- 陈式太极拳 (CTC12) 和广场舞 (SD) 与老年人的适度认知益处有关.
- 显著的生理变化,包括SMM和BMR的改变,与这些炼有关.
- 研究结果表明,运动特定的生理模式可能会通过肌肉-大脑轴影响认知结果.
更多相关视频
03:26Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
Published on: March 8, 2024
3.5K
08:53Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
1.6K
相关概念视频
Muscles that Move the Arm
4.7K
Nine muscles are involved in arm movements. Two of these, the pectoralis major and latissimus dorsi, originate from the axial skeleton and are called axial muscles. The other seven originate from the scapula and are called the scapular muscles.
The pectoralis major has two origins. Its clavicular head originates on the medial half of the clavicle. In contrast, the sternocostal head originates on the costal cartilages of ribs 1-6, the sternum, and the aponeurosis of the external oblique of the...
The pectoralis major has two origins. Its clavicular head originates on the medial half of the clavicle. In contrast, the sternocostal head originates on the costal cartilages of ribs 1-6, the sternum, and the aponeurosis of the external oblique of the...
4.7K
Exercise and Muscle Performance
2.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.3K
Mechanical Protein Functions
5.5K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.
5.5K
Community Based Intervention
288
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
288
Transducer Mechanism: Enzyme-Linked Receptors
3.9K
Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:
Major types that are helpful drug targets include:
3.9K
Hypothalamic-Pituitary Axis
65.8K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.8K
