一天的诱导时间影响劳动的总持续时间
Kylie Cataldo1, Robert Long2, Isoken Olomnu3
1Department of Pediatrics; Department of Obstetrics, Gynecology, and Women's Health. University of Missouri. Columbia, MO, 65212, USA.
American journal of obstetrics & gynecology MFM
|January 23, 2026
概括
当在清晨开始时,诱导分娩 (IOL) 持续时间较短. 劳动诱导的最佳时间,受BMI和平价的影响,不会增加不良结果.
科学领域:
- 产科和妇科 产科和妇科
- 循环节生物学 日间生物
- 生殖医学 生殖医学
背景情况:
- 自发分娩表现出昼夜模式,在晚上晚些时候/早晨达到顶峰.
- 劳动诱导时间对劳动持续时间和结果的影响尚未得到充分理解.
- 假设:劳动诱导时间影响诱导时间和剖腹产风险.
研究的目的:
- 确定劳动诱导时间 (TOI) 是否影响劳动诱导 (IOL) 持续时间和分娩结果.
- 调查母亲的BMI和平价等因素是否会调节TOI的影响.
- 分析TOI,IOL持续时间,剖腹产和新生儿结果之间的关联.
主要方法:
- 对3363个经过诱导 (2019-2022) 的终期怀孕进行了回顾性队列研究.
- 诱导时间是由第一个宫成熟剂或催产素的管理定义的.
- 分析了IOL持续时间,剖腹产率和新生儿结局,使用多变量和生存分析.
主要成果:
- IOL持续时间显示出显著的昼夜节律,随着较晚的诱导时间 (高峰时间为23:00小时,持续时间为21.0小时) 延长.
- 早晨的诱导导致与深夜的诱导相比,工期缩短了多达6小时.
- 最佳的TOI因BMI和平价而异,影响了零度肥胖和平度肥胖个体的出生概率.
- 诱导时间与剖腹产分娩率降低相关,但未增加NICU入院或新生儿不良后果.
结论:
- 在清晨早些时候启动劳动诱导显著缩短了IOL持续时间.
- 对托伊的控制没有显示增加对母亲或胎儿的不良结果.
- 劳动诱导的最佳时间应该考虑个体BMI和平价.
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