家庭亲肠道营养中的维生素K:它真的必要吗?
Estrella Diego1, María Del Carmen Farnández1, Beatriz de León1
1Servicio de Endocrinología y Nutrición, H. U. Cruces, Barakaldo, Spain.
Endocrinologia, diabetes y nutricion
|January 23, 2026
概括
将维生素K添加到肠道营养多种维生素中导致80%的患者的维生素K水平升高. 停用了多种维生素,使家庭亲肠道营养患者的维生素K水平正常化.
科学领域:
- 临床营养学 临床营养学
- 微营养素管理 微营养素管理
- 父母肠道营养治疗疗法
背景情况:
- 亲肠道营养 (PN) 需要适当的微量营养素覆盖,包括维生素K,根据ESPEN指南.
- 添加维生素K的多维生素制剂旨在确保接受PN的成年人摄入足够的维生素K.
研究的目的:
- 在补充含有维生素K的多种维生素后,在接受家庭亲肠营养 (HPN) 的患者中监测维生素K水平.
- 评估富含维生素K的多种维生素对患者维生素K状态的影响.
主要方法:
- 在开始服用多种维生素并添加维生素K6个月后,对HPN患者的维生素K水平进行了分析.
- 这项研究于2021-2022年在Cruces大学医院进行,涉及8名肠道衰竭患者.
主要成果:
- 80% (6/8) 的HPN患者在补充后表现出维生素K水平升高 (平均4.4μl/L).
- 患者因短肠综合征,粘膜疾病或动力障碍而出现肠衰竭.
结论:
- 补充含有维生素K的多种维生素导致HPN患者的维生素K水平超过治疗水平.
- 停用维生素K丰富多维生素和恢复常规多维生素使维生素K水平正常化.
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