相关实验视频
Updated: Jan 25, 2026

07:04
High Precision Zinc Isotopic Measurements Applied to Mouse Organs
Published on: May 22, 2015
7.8K
一种新且高效的单列分离程序,用于通过MC-ICP-MS高精度确定同位素比率分析的MC-ICP-MS
Bingyu Peng1, Qiaohui Zhong1, Feiyu Dong2
1State Key Laboratory of Deep Earth Processes and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Analytica chimica acta
|January 23, 2026
概括
一种新的单列方法通过避免危险的试剂和复杂的步骤来简化 (Mo) 同位素分析. 这种安全高效的技术为包括生物材料在内的各种样品类型提供了高精度.
科学领域:
- 地质化学 地质化学
- 分析化学 分析化学
- 地球科学 地球科学 地球科学
背景情况:
- 传统的 (Mo) 同位素分离方法通常涉及危险的酸 (HF) 和氧化还原试剂,或多列程序.
- 这些传统技术存在安全隐患和操作复杂性,限制了它们的广泛应用.
- 需要更安全,更简单,更有效的方法来进行高精度的Mo同位素测量.
研究的目的:
- 开发一种安全高效的单列分离 (Mo) 的方法.
- 为了实现高精度的Mo同位素测量,而不使用酸 (HF) 或氧化还原试剂.
- 为各种地质和生物样本验证该方法.
主要方法:
- 开发了一种使用内部TOPO树脂的新型单列分离技术.
- 该方法采用稀释的HCl-HNO3介质,避免使用HF和氧化还原试剂.
- (Mo) 被选择性地吸附到TOPO树脂上进行净化.
主要成果:
- 开发的方法实现了有效的矩阵去除,高Mo回收 (>93%),低程序空白 (<0.50 ng).
- 对于标准材料,获得了比±0.06‰ (2SD) 更好的外部可重复性.
- 在生物参考材料中观察到显著的同位素变化 (1.44‰),报告了新的δ98/95MoNIST SRM 3134值.
结论:
- 公司内部的TOPO树脂基程序为Mo同位素的确定提供了更简单,更安全和更有效的替代方案.
- 该方法表现出良好的性能,运行安全性和适用于各种样本矩阵的适用性.
- 报告的生物材料Mo同位素值为质量保证和实验室间比较提供了宝贵的参考.
相关概念视频
Isotopes
63.5K
Elements have a set number of protons that determines their atomic number (Z). For example, all atoms with eight protons are oxygen; however, the number of neutrons can vary for atoms of the same element. The sum of the number of protons and the number of neutrons is the mass number (A). Atoms with the same atomic number but different mass numbers are called isotopes. Elements can have multiple isotopes, for example, carbon-12, carbon-13, and carbon-14.
An element's atomic mass, or weight,...
An element's atomic mass, or weight,...
63.5K
Column Efficiency: Plate Theory
2.0K
Band broadening in a chromatography column is measured by its efficiency. This is determined by the number of theoretical plates (N). Theoretical plate theory states that a separation column consists of a continuous series of imaginary plates where solute equilibration occurs between stationary and mobile phases.
A higher number of theoretical plates signifies better column efficiency and improved separation capabilities. Plate height affects bandwidth and separation quality; it is inversely...
A higher number of theoretical plates signifies better column efficiency and improved separation capabilities. Plate height affects bandwidth and separation quality; it is inversely...
2.0K
Column Efficiency: Rate Theory
923
The rate theory of chromatography provides quantitative insight into the shapes and widths of elution bands. These bands are based on the random-walk mechanism governing molecular migration within a column. The Gaussian profile of chromatographic bands arises from the cumulative effect of random molecular motions as they progress through the column.
During elution, a solute molecule experiences numerous transitions between stationary and mobile phases, exhibiting irregular residence times in...
During elution, a solute molecule experiences numerous transitions between stationary and mobile phases, exhibiting irregular residence times in...
923
Elements: Chemical Symbols and Isotopes
125.5K
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
125.5K
Isotopes and Radioisotopes
11.3K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
An isotope containing...
11.3K
Odds Ratio
1.8K
The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
1.8K

