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Updated: Jan 25, 2026

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在体内CRISPR查确定了SAGA复合体成员作为血液形成的关键调节者

Archana Shankar1,2,3, Leonid Olender4,5, Ian Hsu5

  • 1Graduate Program in Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Nature communications
|January 23, 2026
PubMed
概括

包括Tada2b和Taf5l在内的SAGA复合体对于血液生产 (血液形成) 是至关重要的. 它的破坏抑制了这个过程,导致未成熟的细胞积累并影响疾病模型.

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