基于框架的与机器人辅助的立体脑活检的诊断产量和安全性:匹配的队列分析
Charles-Henry Mallereau1,2, Julien Todeschi3, Lucia Nichelli4
1Sorbonne University, Department of Neurosurgery, La Pitié-Salpêtrière Hospital, AP-HP, Paris, France. mallereau.charles@gmail.com.
Neurosurgical review
|January 23, 2026
概括
基于框架和机器人辅助的立体脑活检提供了类似的诊断准确性. 机器人辅助程序有更多的临时并发症,但这两种方法对脑活检都是安全的.
科学领域:
- 神经外科 神经外科
- 医疗技术 医疗技术 医学技术
- 诊断程序 诊断程序 诊断程序
背景情况:
- 基于框架的立体活检是大脑活检的既定标准.
- 机器人辅助的立体战术技术正在成为替代方案.
- 这些脑活检方法的比较数据有限.
研究的目的:
- 为了比较基于框架的诊断产量和并发症率与机器人辅助的立体脑活检.
- 评估这两种立体活检方法的疗效和安全性.
- 为神经外科的临床决策提供数据.
主要方法:
- 对接受立体脑活检 (2011-2019) 的成年患者进行了回顾性,双中心的比较分析.
- 匹配的队列方法:230个机器人辅助病例与1:2匹配的460个基于框架的病例.
- 匹配标准包括病变位置,大小,对比度增强,组织病理学和患者年龄.
主要成果:
- 基于框架和机器人辅助技术的相同诊断收益率为97.4%.
- 在两组中,非诊断性活检率为2.6%.
- 在机器人辅助组 (6.5%) 和基于框架的 (2.8%) 中,症状暂时并发症率更高,p=0.02.
- 在严重并发症 (如出血,感染,发作,永久性缺陷或死亡率) 中没有显著差异.
结论:
- 基于框架和机器人辅助的立体活检证明了同等的诊断疗效.
- 机器人辅助活检显示过渡性症状并发症的比率更高,但严重结果的安全性概况类似.
- 技术选择取决于外科医生的经验,资源和工作流集成.
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