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Updated: Jan 25, 2026

Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells
05:02

Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells

Published on: February 4, 2021

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可溶性E-cadherin-CXCL1-CXCR2轴作为炎症性乳腺癌脑转移中的治疗脆弱性

Xiaoding Hu1,2, Yun Xiong3, Emilly S Villodre1,2

  • 1Departments of Breast Medical Oncology.

Neuro-oncology
|January 23, 2026
PubMed
概括

溶性E-cadherin (sEcad) 通过增加癌细胞入侵和促进炎症性大脑环境,驱动炎症性乳腺癌中的大脑转移. 用CXCR2抑制剂向CXCL1/CXCL8-CXCR2通路可能会减少大脑转移.

关键词:
大脑转移的转移.在CXCL1-CXCR2之间.炎症性乳腺癌 (IBC) 是一种转移性 IBC 是一种转移性 IBC.可溶性E-cadherin (sEcad) 是一种可溶性E-cadherin.

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