口腔手术中低水平激光疗法:改善术后结果的证据有多强?
1NIHR Academic Clinical Lecturer in Oral Surgery, Peninsula Dental School, University of Plymouth, Plymouth, UK. araz.ahmed@plymouth.ac.uk.
Evidence-based dentistry
|January 23, 2026
概括
低水平激光疗法 (LLLT) 加快治愈,减少口腔手术后的疼痛. 虽然在早期治愈和缓解疼痛方面有效,但证据质量受到研究异质性和短期随访的限制.
科学领域:
- 在口腔外科手术.
- 生物光子学 生物光子学
- 再生医学是一种再生医学.
背景情况:
- 手术后的疼痛和延迟愈合是口腔外科手术中常见的挑战.
- 低水平激光疗法 (LLLT) 正在探索其减轻这些问题的潜力.
研究的目的:
- 在口腔外科手术中系统审查LLLT疗效的随机对照试验 (RCT).
- 评估LLLT对术后愈合和患者舒适性的影响.
主要方法:
- 按照PRISMA 2020指南进行系统审查.
- 包括18个RCT,有771名参与者接受各种口腔外科手术.
- 使用Cochrane RoB 2工具评估偏差风险;使用PROPS框架解释临床相关性.
主要成果:
- LLLT显著增强了早期的上皮质化和软组织愈合,特别是在660-810纳米波长和3-12 J/cm2流动下.
- 观察到炎症性细胞因子的减少和血管内皮生长因子的增加.
- 在第一周内,术后疼痛得分下降了30-55%,感染等并发症也减少了.
结论:
- 在口腔外科手术后,LLLT在加速早期愈合和减少术后疼痛方面表现有前途.
- 没有报告任何显著的不良影响,但有一些证据表明并发症率降低.
- 在LLLT参数的异质性,小样本大小和有限的长期随访减少了对证据确定性的信心.
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