双A从商业可用的乳头迁移:HPLC-FLD分析和婴幼儿暴露评估
Lena Herwanger1, Katharina Sternecker2, Jan Kühnisch1
1Department of Conservative Dentistry, Periodontology and Digital Dentistry, LMU University Hospital, LMU Munich, Goethestrasse 70, 80336, Munich, Germany.
Environmental science and pollution research international
|January 23, 2026
概括
双甲 (BPA) 可以从乳头上迁移,即使是那些标有"无BPA"的乳头. 即使是最低的迁移水平也超过了新的安全限制,对婴儿和幼儿构成风险.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 儿科健康 儿科健康
背景情况:
- 双A (BPA) 是塑料中发现的一种内分泌干扰化学物质,与各种健康问题有关.
- 由于未成熟的排毒系统和关键发育阶段,婴儿和幼儿对BPA非常敏感.
- 虽然欧盟在婴儿奶瓶中限制了BPA,但尽管有误导性的"无BPA"标签,但BPA在乳头中的存在仍然不受管制.
研究的目的:
- 为了量化BPA从商业可用的乳头迁移.
- 根据欧洲食品安全局 (EFSA) 的可容忍每日摄入量 (TDI),评估婴儿暴露于乳头中的BPA.
主要方法:
- 乳头被切成组件 (盾牌,乳头) 并切成碎片.
- 使用高性能流体染色学与光检测 (HPLC-FLD) 分析了BPA迁移.
- 每个乳头的额外推算的BPA总释放量被计算并与EFSA TDI进行了比较.
主要成果:
- 化物中的BPA度范围高达288微克/升.
- 每个乳头的BPA总释放量从33到26,536 ng不等.
- 在标有"无BPA"的产品中检测到的BPA迁移率最高.
- 即使是最低的BPA迁移也超过了2023年EFSA的TDI (0.2 ng/kg bw/day).
结论:
- 乳头可以成为早期BPA暴露的重要来源.
- 乳头上的自愿"无BPA"声明是不可靠的.
- 需要对乳头中的BPA进行协调的欧盟监管,类似于对奶瓶和玩具的限制.
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