在CAD/CAM陶牙科修复中生存率:一个元分析
1College and Hospital of Stomatology, Guangxi Medical University, Nanning, China.
Medicine
|January 24, 2026
概括
计算机辅助设计/计算机辅助制造陶牙科修复显示出高的生存率,随机对照试验的综合率为96%. 需要进一步的研究来证实临床有效性,因为队列研究中的异质性.
科学领域:
- 牙科 牙科是指牙科的专业.
- 生物材料科学 生物材料科学
- 数字健康数字健康
背景情况:
- 评估现代牙科假肢的长期成功至关重要.
- 计算机辅助设计/计算机辅助制造 (CAD/CAM) 已经彻底改变了陶修复制造业.
研究的目的:
- 系统地审查和评估CAD/CAM陶牙科修复的生存率.
- 综合来自随机对照试验 (RCT) 和队列研究的证据.
主要方法:
- 系统审查遵循PRISMA指南,并预先注册了协议 (PROSPERO:CRD42024599053).
- 搜索了MEDLINE,Scopus和Cochrane中央注册 (2000年至2024年5月),包括参考列表.
- 包括具有≥1年随访期的RCT和队列研究;分析了25项研究 (13个RCT,12个队列).
主要成果:
- 最初的搜索产生了714篇文章;25项研究符合纳入标准.
- 在RCT中CAD/CAM陶修复的综合存活率为96% (95%CI:94-98%).
- 在RCT中观察到的低异质性 (I2=23%),在队列研究中观察到的显著异质性.
结论:
- 在RCT和队列研究中,CAD/CAM陶修复显示了高的生存率.
- 虽然有希望,但建议进行进一步的大规模RCT来巩固临床有效性,特别是考虑到队列数据的异质性.
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