心理症状和不良童年经历对共存的阻塞性排便和便失禁症状产生负面影响
Elisa Karhu1, Brooke Gurland2, Meredith R Craven1
1Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.
童年不良经历 (ACE) 和心理症状显著影响受阻排便的严重程度. 抑郁症得分与排便障碍和便失禁相关,这表明这些共同存在的疾病有不同的机制.
科学领域:
- 胃肠病学 胃肠病学
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 阻塞性排便经常与便失禁同时发生.
- 心理因素对这些综合症状的影响尚不清楚.
- 调查不良童年经历 (ACE) 和心理困扰对于了解症状严重程度至关重要.
研究的目的:
- 检查ACE和心理症状与同时存在阻塞性排便和便失禁的严重性之间的关联.
- 探索基于心理因素的病理生理机制的潜在差异.
主要方法:
- 对128名患有阻塞性排便症状的患者的前性注册表的回顾性分析.
- 使用了验证的调查:医院焦虑和抑郁量表 (HADS) 和ACE问卷.
- 评估了临床特征,包括使用Renzi阻塞排便综合征 (ODS) 和克利夫兰诊所便失禁 (CCFI) 评分的症状严重程度.
主要成果:
- 47%的患者报告ACE;49%的HADS焦虑≥8,28%的HADS抑郁≥8.
- ACE与更严重的ODS得分相关,但不是CCFI得分.
- 经过年龄调整后,较高的抑郁症得分与ODS和CCFI得分的严重程度有显著的相关性. 年轻的患者报告了更多的ACE和更高的症状严重程度.
结论:
- ACE和心理症状似乎通过不同的途径影响受阻排便和便失禁.
- 了解这些差异可能有助于制定有针对性的治疗策略.
- 针对年龄的具体考虑对于管理这些复杂的疾病很重要.
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