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Updated: Jan 25, 2026

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
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Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices

Published on: May 9, 2018

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抑制N-乙乙胺酸胺酶可降低SARS-CoV-2感染在人类精确切割肺切片和下调NF-KBB信号传输

Veronica La Rocca1,2, Carolina Filipponi1, Viktoria Diesendorf3

  • 1Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Journal of medical virology
|January 24, 2026
PubMed
概括

抑制N-乙氨酸胺基酶 (NAAA) 增加了棕甲胺 (PEA) 水平,通过阻断核因子-κB (NF-κB) 激活来抑制SARS-CoV-2复制和炎症. 这突出了NAAA作为病毒复制的关键宿主因素.

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