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相关概念视频

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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What is Metabolism?00:52

What is Metabolism?

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Overview
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¹H NMR of Labile Protons: Deuterium (²H) Substitution00:48

¹H NMR of Labile Protons: Deuterium (²H) Substitution

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This lesson illustrates the role of deuterium substitution in simplifying the NMR spectrum of compounds comprising labile protons. One method employed is the use of deuterium. Amongst the three isotopes of hydrogen, deuterium (2H) has a nucleus composed of one proton and one neutron. When the D2O solvent is added to a pure dry ethanol solution, its labile proton is substituted with deuterium.
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Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

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Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
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Carbohydrate Metabolism01:36

Carbohydrate Metabolism

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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
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Metabolic Rate01:25

Metabolic Rate

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The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
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相关实验视频

Updated: Jan 25, 2026

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
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在代谢成像中使用先进的方法.

Fabian Niess1, Bernhard Strasser2, Bernard Lanz3,4

  • 1High-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria. fabian.niess@meduniwien.ac.at.

Magma (New York, N.Y.)
|January 24, 2026
PubMed
概括

代谢成像 (DMI) 推进了基于MR的代谢途径测绘,使用安全的追踪剂. 这篇评论详细介绍了硬件,采购和重建改进,将DMI定位为疾病研究的关键工具.

关键词:
的代谢成像学 的代谢成像学标有标签的标记剂.动态建模 动态建模代谢映射是指代谢的映射多核MR光谱学 多核MR光谱学

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科学领域:

  • 磁共振成像 (MRI) 是一种磁共振成像技术.
  • 代谢成像 - 代谢成像
  • 医学物理 医学物理

背景情况:

  • 代谢成像 (DMI) 是一种多用途的MRI技术,用于体内代谢途径的映射.
  • 它使用安全的,非电离的2H标记的标记剂.

研究的目的:

  • 总结过去十年DMI的方法进步.
  • 涵盖硬件,采购,重建和量化发展.

主要方法:

  • 多核系统修改和双调线圈用于3D DMI.
  • 有效的空间频谱编码和基于SSFP的平衡MRSI,以改善SNR和分辨率.
  • 暂时交错的1H/2H收购和间接的1H观察探测 (QELT).
  • 用人工智能驱动和基于模型的重建方法来消除和加速采样.

主要成果:

  • 在临床和超高强度的场强度下,3D DMI 已启用.
  • 实现了提高SNR效率和时空分辨率.
  • 将DMI整合到标准的MRI工作流程中变得更加容易.
  • 开发了强大的光谱-时间合适和无雾化方法.

结论:

  • DMI为度估计和动力建模提供了有希望的策略.
  • 解决标签丢失对于准确量化至关重要.
  • DMI补充了FDG-PET和13C-MRS用于研究神经,瘤和全身疾病.