心血管风险因素及其管理的性别差异
Lale Tokgozoglu1, Meral Kayıkcioglu2, Jeanine Roeters van Lennep3
1Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Atherosclerosis
|January 24, 2026
概括
动脉样硬化心血管疾病 (ASCVD) 影响两性,但风险因素和结果的性别特异性需要量身定制的方法. 解决知识差距和改善妇女的预防护理对于减少ASCVD负担至关重要.
科学领域:
- 心脏病学 心脏病学
- 血管生物学 血管生物学
- 医学中的性别差异.
背景情况:
- 动脉样性心血管疾病 (ASCVD) 是全球主要的死亡原因.
- 在ASCVD风险因素,病理生理学,临床表现和治疗结果方面存在显著的性别差异.
- 当前的理解和管理策略往往无法充分解决这些性别特异性的细微差别.
研究的目的:
- 审查两性中ASCVD风险的生物和性别相关驱动因素.
- 突出影响ASCVD的女性特异性因素,包括妊娠并发症和更年期.
- 识别知识差距,倡导改善ASCVD妇女的研究和护理.
主要方法:
- 对ASCVD现有证据的综合文献综述.
- 对主要风险因素 (高血压,脂质失调,糖尿病,肥胖,吸烟,炎症) 患病率和影响的性别特异性的分析.
- 检查女性特异性因素及其在ASCVD发展和进展中的作用.
主要成果:
- 审查确定了ASCVD风险因子流行率和疾病机制的性别特异性模式.
- 女性特有的因素,如怀孕并发症和更年期显著影响ASCVD风险.
- 妇女在研究中的代表性不足,治疗惯性和预防性护理差距有助于妇女的不理想结果.
结论:
- 细微的理解和针对性别的管理对于有效的ASCVD预防和治疗至关重要.
- 迫切需要增加研究,重点关注妇女的心血管健康.
- 在研究和临床实践中解决系统性问题对于减少女性ASCVD负担至关重要.
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