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Updated: Jan 26, 2026

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在积极监测队列中,跨直肠和跨关节前列腺活检之间的癌症检测比较
Sunny B Nalavenkata1, Amy L Tin2, Chris D Gaffney3
1Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Urology, Westmead Hospital, University of Sydney, Sydney, Australia.
European urology focus
|January 24, 2026
概括
跨 (TP) 前列腺活检和跨直肠 (TR) 活检显示了类似的总体高度癌症检测率. 然而,TP活检更好地检测前部瘤,而TR活检对后部瘤更有效.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 由于感染风险较低,越来越多地喜欢跨膜 (TP) 前列腺活检而不是跨直肠 (TR) 活检.
- 在TP和TR活检方法之间对癌症检测率的比较数据有限.
研究的目的:
- 为了比较TP和TR前列腺活检方法之间的癌症检测率和疾病位置.
- 在从TR过渡到TP活检期间分析大型机构队列.
主要方法:
- 分析了来自1304名正在积极监测中的患者的1387例活检.
- 包括人口统计,活检方法,组织病理学和MRI发现.
- 主要结局:检测高度癌症 (格里森等级组≥2),使用多变量逻辑回归分析.
主要成果:
- 在总体高度癌症检测中没有显著差异 (TP: 39%与TR: 37%).
- TP活检显示前部高度疾病的产量更高 (21%vs9%).
- TR活检显示后部高度疾病的产量更高 (34%vs28%).
结论:
- 总的来说,高度癌症检测率在TP和TR活检之间是可比的.
- 对于检测前前列腺瘤,TP活检优越,而TR活检对后部瘤更好.
- 需要进一步的研究,包括使用MRI的随机试验,以澄清特定位置的检测差异.
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