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综合性比较单个和多个祖先的多基因分数方法与PGS-Hub平台的综合比较.

Xingyu Chen1,2,3,4,5, Fei Wang6,7, Hongqiang Zhao1,2

  • 1China National Center for Bioinformation, Beijing, China.

Nature communications
|January 24, 2026
PubMed
概括

这项研究对13种复杂特征的多基因评分 (PGS) 方法进行了基准测试. LDpred2在单个祖先预测方面表现出色,而LDpred2-multi在多个祖先性能方面领先,具有新的平台,PGS-hub,简化了PGS计算.

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