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Updated: Jan 26, 2026

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NONO-HOXA1-Wnt轴在心肌细胞分化中的重要作用

Zhiyu Feng1, Yuan Gao1, Han Gao1

  • 1Shanghai Key Laboratory of Birth Defects, Pediatric Heart Center, Children's Hospital of Fudan University, Shanghai, China.

Nature communications
|January 24, 2026
PubMed
概括

NONO蛋白对于心脏发育至关重要. 它的缺乏通过影响HOXA1和Wnt信号来损害心肌细胞分化,为与NONO突变相关的先天性心脏病提供了洞察力.

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