1级压力损伤的糖尿病患者的临床特征和相关并发症,基于TrinetX回顾性研究
Ya-Huei Chen1, Pi-Hua Chang1, Mei-Yu Chang1
1Department of Nursing, Taichung Veterans General Hospital, Taichung, Taiwan.
Scientific reports
|January 24, 2026
概括
患有第一阶段压力损伤 (PI) 的糖尿病患者面临更高的外周动脉封闭性疾病 (PAOD) 和截肢的风险. 早期PI查对于管理糖尿病并发症和改善患者结果至关重要.
科学领域:
- 内分泌学和新陈代谢学
- 血管外科 血管外科
- 精神病学是一个精神病学.
背景情况:
- 糖尿病带来了重大的全球健康挑战.
- 压力损伤 (PI),外围动脉封闭性疾病 (PAOD),截肢和精神疾病等并发症严重影响糖尿病患者的生活质量和医疗保健利用率.
研究的目的:
- 调查糖尿病患者1期PI,PAOD,截肢和精神疾病之间的关联.
- 为改善管理糖尿病相关并发症的临床策略提供信息.
主要方法:
- 使用TrinetX多中心数据从2014年到2023年进行的回顾性队列研究.
- 对有或没有第一阶段PI的糖尿病患者的分析.
- 卡普兰-梅尔生存分析以估计危险比率 (HRs) 和6个月全因死亡率.
主要成果:
- 在7697名糖尿病患者中,第一阶段PI与PAOD (2.74至2.90) 和截肢 (2.74至4.24) 的HR增加有关.
- 精神疾病风险略有下降 (HR从1.91降至1.88),死亡率有所降低.
- 死亡率显示PAOD和截肢的最小变化,但精神疾病的适度减少.
结论:
- 糖尿病患者的第一级PI与PAOD和截肢的风险增加有关.
- 在患有第1期PI的糖尿病患者中,观察到精神疾病的风险略低.
- 强调早期查和预防措施对于风险糖尿病患者的必要性,以减轻并发症和改善健康结果.
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