乳腺癌手术等待时间和COVID-19:加拿大基于人口的分析
1Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Annals of surgical oncology
|January 24, 2026
概括
COVID-19大流行严重影响了乳腺癌 (BC) 手术等待时间,诊断至手术间隔较长,但后辅助治疗等待时间较短. 这突出了大流行期间BC护理的分类.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 外科手术的结果
背景情况:
- 由于COVID-19大流行导致手术室限制,需要对乳腺癌 (BC) 手术进行分拣.
- 这项研究调查了大流行病对BC外科等待时间的影响.
研究的目的:
- 为了评估COVID-19流行病对乳腺癌手术等待时间的影响.
- 分析不同流行病阶段新辅助疗法使用和手术时间的变化.
主要方法:
- 这是一项基于人口的队列研究,在2018年1月至2021年12月期间,在加拿大安大略省诊断出BC的37520名患者中进行.
- 患者被分为大流行前,大流行后和大流行前的三组.
- 时间到事件分析用于评估第一次BC手术的时间,对新辅助化疗 (NAC) 和新辅助内分泌疗法 (NET) 的子组分析.
主要成果:
- 与大流行前时期相比,每月接受BC手术的概率在即时和大流行期间显著下降.
- 与大流行前期相比,NAC和NET的使用在即时流行期间显著增加 (NAC:24.3%对14.4%;NET:12.4%对6.6%).
- 对于接受手术作为第一项治疗的患者,与大流行前和大流行期间 (1.2 个月) 相比,即时流行 (1.0 个月) 的中位等待时间最短.
结论:
- 由于COVID-19大流行,乳腺癌患者的诊断至手术时间更长.
- 疫情期间观察到新辅助疗法的使用增加.
- 尽管整体等待时间较长,但在新辅助疗法后的外科等待时间在即时流行期间较短,这表明了护理的分拣.
相关概念视频
Analysis of Population Pharmacokinetic Data
696
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
696
Population Growth
28.1K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.1K
Conservation of Small Populations
16.7K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
16.7K
What is Population Genetics?
64.5K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.5K
Cancer Survival Analysis
659
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
659
What are Populations and Communities?
37.4K
Overview
37.4K


