在中风后认知障碍中基于BCI的非侵入性认知康复:随机对照试验的研究协议
Xinyue Niu1, Min Yuan2, Jie Zhang3
1School of Preclinical Medicine and School of Nursing, Chengdu University, Chengdu, China.
Trials
|January 24, 2026
概括
这项研究研究了针对中风后认知障碍 (PSCI) 的非侵入性脑电脑界面 (BCI) 认知训练. 在中风幸存者中,BCI神经反可以改善认知功能和神经可塑性.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 生物医学工程 生物医学工程
背景情况:
- 脑卒中后认知障碍 (PSCI) 显著影响生活质量和生存.
- 目前针对PSCI的干预措施在有效性和可访问性方面存在局限性.
- 非侵入性脑电脑接口 (BCI) 技术为增强神经可塑性和认知恢复提供了潜在的途径.
研究的目的:
- 评估基于BCI的认知训练对PSCI的有效性.
- 探索由BCI促进的认知恢复的潜在神经机制.
- 建立BCI作为一个安全和可访问的工具,用于中风后的认知康复.
主要方法:
- 一项前性,随机,双盲,受控试验,对66名PSCI患者进行.
- 干预组接受BCI认知训练,每周5天,持续4周.
- 评估包括MoCA分数,认知功能,神经生理学标志物和基线,干预后和3个月后续的日常生活功能.
主要成果:
- 主要结局:干预后4周MoCA得分的变化.
- 二次结果:在3个月的随访期内持续的认知改善.
- 探索神经生理学标记,以阐明BCI对神经可塑性的影响.
结论:
- 预计结果将证明BCI在PSCI中的临床实用性.
- 将提供证据证明BCI在调节神经可塑性机制中的作用.
- 研究结果将为中风幸存者提供个性化的神经康复策略.
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