细胞表面的定位和细胞外蛋白酶的功能来自乳酸细菌株的乳酸细菌菌株
Youwei Ji1, Xiang Lu1, Kaige Zheng1
1State Key Laboratory for Quality and Safety of Agro-Products, Key Laboratory for Food Microbiology and Nutrition of Zhejiang Province, College of Food Science and Engineering, Ningbo University, Ningbo, Zhejiang, P. R. China.
Critical reviews in food science and nutrition
|January 25, 2026
概括
乳酸细菌是一种乳酸细菌.
科学领域:
- 微生物学 微生物学
- 生物化学 生物化学
- 食品科学 食品科学 食品科学
背景情况:
- 乳酸细菌 (LAB) 拥有复杂的蛋白质溶解系统,对于营养获取和产品开发至关重要.
- 细胞包膜蛋白酶 (CEPs) 是LAB中的关键酶,能将素化成和氨基酸.
研究的目的:
- 审查LAB细胞包膜蛋白酶 (CEPs) 的生物合成,成熟,调节和应用.
- 突出CEP多样性,宿主相互作用和衍生的健康应用的新见解.
主要方法:
- 文献评论综合了关于CEP的当前知识.
- 对监管机制和基因工程策略的分析.
- 探索对CEP主机交互的omics驱动的见解.
主要成果:
- 在LAB中,CEP对于味道,质地,生物活性释放和宿主相互作用至关重要.
- 不同的监管机制控制CEP的表达,与菌株特定的变化.
- 奥米克斯方法揭示了复杂的CEP主机交互.
结论:
- CEP为功能性食品创新和治疗开发提供了巨大的潜力.
- 需要进行进一步的研究,以克服临床应用中稳定性和生物可用性的挑战.
相关概念视频
Outer Layers of the Cell Envelope
993
The outermost layers of prokaryotic cells play a critical role in their survival, virulence, and interaction with the environment. These layers, often composed of polysaccharides, polypeptides, or proteins, form protective and adhesive structures that vary in organization and function.Capsules and Slime LayersCapsules are highly organized, tightly bound layers that firmly attach to the bacterial cell wall. Capsules are usually made of polysaccharides, though some are made of polypeptides. These...
993
Cell-surface Signaling
54.0K
Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.
54.0K
Acidity and Basicity of Carboxylic Acid Derivatives
4.2K
Carboxylic acids are the strongest among organic acids, as they readily lose the hydroxyl proton to form a resonance-stabilized carboxylate ion. In comparison, the acid derivatives lack acidic hydrogens directly attached to a functional group. In these compounds, the acidic nature arises from their ability to lose α hydrogens, making them weakly acidic.
The relative acidic strength of the derivatives can be explained based on the extent of resonance stabilization of the conjugate base. The...
The relative acidic strength of the derivatives can be explained based on the extent of resonance stabilization of the conjugate base. The...
4.2K
Structures of Carboxylic Acid Derivatives
3.7K
Structure of Carboxylic Acid Derivatives
Carboxylic acid derivatives contain an acyl group attached to a heteroatom such as chlorine, oxygen, or nitrogen. The carbonyl carbon and oxygen are both sp2-hybridized with an unhybridized p orbital.
The three sp2 orbitals of the carbonyl carbon form three σ bonds, one each with the carbonyl oxygen, the α carbon, and the heteroatom, whereas the other two sp2 orbitals of the carbonyl oxygen are occupied by the lone pairs. Further, the unhybridized p...
Carboxylic acid derivatives contain an acyl group attached to a heteroatom such as chlorine, oxygen, or nitrogen. The carbonyl carbon and oxygen are both sp2-hybridized with an unhybridized p orbital.
The three sp2 orbitals of the carbonyl carbon form three σ bonds, one each with the carbonyl oxygen, the α carbon, and the heteroatom, whereas the other two sp2 orbitals of the carbonyl oxygen are occupied by the lone pairs. Further, the unhybridized p...
3.7K
Spectroscopy of Carboxylic Acid Derivatives
3.0K
Infrared spectroscopy is primarily used to determine the types of bonds and functional groups. In carboxylic acid derivatives, a typical carbonyl bond absorption is observed around 1650–1850 cm−1. For esters, the absorption is recorded at around 1740 cm−1, while acid halides show the absorption at about 1800 cm−1. Another acid derivative, the acid anhydrides, exhibit two carbonyl absorption around 1760 cm−1 and 1820 cm−1, arising from the symmetrical and...
3.0K
Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides
5.9K
Naming Acid Halides
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
5.9K


